Lockhart (Dane DeHaan) is sent to a sanatorium in the Alps to pick up the company CEO who is recuperating here. On the way back, Lockhart suffered a car accident and fractured his left leg. In desperation, he had to stay in a sanatorium to recuperate temporarily. In the nursing home, Lockhart meets the mysterious girl Hannah (Mia Goth). The strange atmosphere in the sanatorium and the successive scientifically unexplainable events that occurred around Lockhart made Lockhart begin to doubt the nature of the sanatorium's operations. The ambiguous relationship between Hannah and the chief physician Sherlock Holmes (played by Jason Isaacs) made Lockhart aware that the incident was not simple. Finally, Lockhart saw through the secret hidden in this sanatorium, and at the same time, his nightmare began.
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